氨酸补充剂调节卵质量和子宫转录基因组在晚期肉养殖者
Mingkun Gao1, Youying Chen1, Xiaomin Li2
1State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Animal nutrition (Zhongguo xu mu shou yi xue hui)
|December 4, 2024
概括
饮食中的氨酸显著改善了 brojler breeder 的蛋质量,提高了其厚度和强度. 氨酸促进的运输和细胞增殖在贝腺,不像HMTBA.
科学领域:
- 动物营养和家禽科学 动物营养和家禽科学
- 生殖生理学 生殖生理学
- 生物化学 生物化学
背景情况:
- 食中含有的甲 (Met) 和其类型的2-基-4-甲) -酸盐 (HMTBA) 对家禽的营养至关重要.
- 了解它们对蛋质量及其潜在生理机制的具体影响对于优化养饮食至关重要.
研究的目的:
- 为了比较饮食中的甲 (Met) 与2-基-4-甲) -酸 (HMTBA) 在 brojler breeder 蛋质量的疗效.
- 阐明Met提高蛋质量的机制,重点关注的微观结构和腺功能.
主要方法:
- 720只WOD188肉繁殖被分为三组,食基质,补充MET或补充HMTBA的饮食7周.
- 评估了蛋质量参数 (形状指数,厚度,强度,性).
- 通过转录组分析评估血清和贝腺和水平,Ca2+ ATPase活性,组织形态学,蛋超结构和基因表达 (OC-116,CALB1,ITM2C).
主要成果:
- 氨酸补充剂显著改善了蛋形状指数,外厚度,破裂强度和断裂性 (P < 0.05).
- 补充HMTBA没有显著改善 (P>0.05).
- 发现血清和贝腺和的增加,贝腺Ca2+ ATPase活动的增强,组织形态的改善和卵超结构的优化. 关键基因 (OC-116,CALB1,ITM2C) 和Wnt/Ca2+信号通路被上调.
结论:
- 饮食中的氨酸有效地提高肉养殖蛋的质量,超过HMTBA.
- 氨酸通过促进运输和细胞在状腺中的增殖来改善蛋质量,由WNT11和CALB1.1调节.
- 这种机制影响沉积和蛋超结构的发展.
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