儿科患者的治疗性血交换:来自单一中心的结果
Tahir Dalkiran1, Mehmet Mercan2, Sevcan Ipek3
1Department of Pediatric Intensive Care, Necip Fazil City Hospital, Kahramanmaras, Türkiye.
Journal of pediatric intensive care
|December 4, 2024
概括
治疗性血交换 (TPE) 对患有各种疾病的儿科患者有效. 这项研究对25名儿童进行了128次TPE治疗,强调了它在血液学,神经学和自身免疫性疾病中的应用.
科学领域:
- 儿科血液学 儿科血液学
- 儿科神经学 儿科神经学
- 儿科脏病学 儿科脏病学
- 儿科风湿病学 儿科风湿病学
- 临界护理医学 临界护理医学
背景情况:
- 治疗性血交换 (TPE) 是几种儿科疾病的成熟治疗方法.
- 它的应用涵盖了血液学,神经学,脏学和自身免疫/风湿性疾病.
- 经验和最新的指导方针对于优化儿科护理中的TPE至关重要.
研究的目的:
- 报告儿童患者治疗性血交换 (TPE) 的机构经验.
- 在儿科队列中分析TPE会话的指示和结果.
- 根据新出现的临床条件,建议对现有的异位症标准进行更新.
主要方法:
- 对儿科患者病历的回顾性审查.
- 分析了2019年至2021年间接受TPE治疗的患者的数据.
- 包括患者的人口统计,TPE指示和会话数量.
主要成果:
- 在25名儿科患者 (平均年龄为59.6个月) 中,共进行了128次TPE治疗.
- 指示包括有/没有MODS的败血症,急性肝衰竭,溶血性尿素综合征 (HUS),自身免疫性溶血性贫血症,多发性硬化症,自身免疫性脑炎和MIS-C.
- 具体的病例包括严重肌痛性肌痛危机,脑膜炎,COVID-19相关的HUS,HLH和代谢障碍.
结论:
- 治疗性血交换是一种可行的治疗选择,用于广泛的儿科疾病.
- 目前的指导方针可能需要修订,以涵盖新认可的条件,如MIS-C.
- 需要进一步的研究来完善儿童群体的TPE协议.
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