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Updated: Jun 5, 2025

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甲基转移酶CbzMT催化了代的3,4-二甲基化,用于卡巴佐米生物合成

Baixin Lin1, Dashan Zhang1, Junbo Wang1

  • 1State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, China.

Engineering microbiology
|December 4, 2024
PubMed
概括

分离和研究了被称为carbazomycins A和B的碳醇衍生物. 一个关键的酶,CbzMT,被确定为它们的生物合成至关重要,使得新的抗真菌化合物的创造成为可能.

关键词:
碳醇是一种碳醇.卡巴佐米辛 (Carbazomycins) 是一种碳酸盐.循序渐进的甲基化在O-甲基转移酶.一个菌株多个化合物 (OSMAC)

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