在老年人中,对位膜透管边缘到边缘的修复 - 一种安全有效的治疗方法
Dominik Felbel1, Michael Paukovitsch1, Matthias Gröger1
1Department of Cardiology, Ulm University Heart Center, Ulm, Germany.
ESC heart failure
|December 4, 2024
概括
过导管边缘到边缘修复 (M-TEER) 是安全的老年患者与 mitra regurgitation (MR),显示与年轻患者相似的一年结果. 然而,老年人三年死亡率较高表明需要加强术后护理.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 老年医学 老年医学
背景情况:
- 随着年龄的增长,心肌吐 (MR) 和并发症的增加.
- 跨导管边缘到边缘修复 (M-TEER) 越来越多地用于老年患者,但数据有限.
- 这项研究分析了M-TEER在80岁和90岁之间的人的现实结果.
研究的目的:
- 与年轻患者相比,评估M-TEER在老年患者 (≥80岁) 的安全性和有效性.
- 为了确定接受M-TEER的老年患者死亡率的预测因素.
主要方法:
- 对1118名接受M-TEER (2010-2021) 的患者进行了回顾性分析.
- 患者分为老年人 (≥80岁) 和年轻人 (<80岁) 组.
- 卡普兰-梅尔和考克斯的比例危险模型用于评估1年和3年死亡率和心力衰竭住院率.
主要成果:
- 老年患者的初级MR发生率较高,但在手术前和手术后的MR程度相似.
- 医院内死亡率和1年全因死亡率在各组之间相似.
- 在老年人中,三年全因死亡率明显高 (43.1%与33.0%相比).
- 较高的NT-proBNP,介入前的MR等级和EuroSCORE II预测了老年人3年死亡率.
结论:
- 对于患有症状的老年MR患者来说,M-TEER是一种安全有效的治疗方法,可提供症状缓解和可比的1年结果.
- 高度EuroSCORE II和晚期心力衰竭的老年患者可能需要额外的护理来降低长期死亡率.
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