在患有先前抑郁症的人群中,加速计衍生的运动行为和死亡风险:前性队列研究
Tingshan Duan1, Zhi Cao2, Xuemei Wang1
1School of Public Health, Hangzhou Normal University, China.
The British journal of psychiatry : the journal of mental science
|December 4, 2024
概括
充足的睡眠,高水平的体力活动和减少久坐时间显著降低了抑郁症患者的死亡风险. 这些生活方式因素对于管理这一群体的长期健康结果至关重要.
科学领域:
- 流行病学 流行病学
- 行为科学 行为科学
- 公共卫生 公共卫生
背景情况:
- 关于身体不活动,久坐不动行为和睡眠不足如何影响抑郁症患者长期健康的证据有限.
- 了解这些行为影响对于改善这个脆弱人群的健康结果至关重要.
研究的目的:
- 通过加速度计测量日常运动行为与死亡风险之间的关联.
- 具体检查睡眠时间,久坐行为,轻度体力活动 (LPA) 和中度至强度体力活动 (MVPA) 在患有抑郁症的个体中.
主要方法:
- 在2013-2015年期间,利用了来自10914名被诊断患有抑郁症的个人 (ICD-10代码F32-F33) 的英国生物库数据.
- 客观测量睡眠,静坐时间,LPA和MVPA,使用连续七天的手腕加速度计.
- 追踪参与者直到2021年,以追踪死亡事件,随访时间中位数为6.9年.
主要成果:
- 在睡眠时间和死亡率之间观察到U形的关联,最佳风险约为每天9小时.
- 无论是LPA和MVPA都显示出与死亡率的L形关联,表明较高的活动水平与较低的风险相关,在每天350分钟 (LPA) 和每天50分钟 (MVPA) 后的回报率下降.
- 久坐时间的增加与死亡风险有关,特别是每天超过8小时. 用LPA或MVPA代替静坐时间显著降低了死亡风险,分别降低了12%和24%.
结论:
- 充足的睡眠时间,较高的体力活动水平和减少的久坐时间与先前存在抑郁症的个体死亡风险较低有关.
- 这些发现强调了促进健康生活方式行为的重要性,以减轻这一群体的长期健康风险.
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