多器官在芯片上用于癌症药物的药理动力学-药理动力学 (PK-PD) 建模和模拟

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Abdurehman Eshete Mohammed1,2, Filiz Kurucaovalı3, Devrim Pesen Okvur4

  • 1Department of Molecular Biology and Genetics, Izmir Institute of Technology, Izmir, Turkey. abdurehman.eshete@wu.edu.et.

Journal of pharmacokinetics and pharmacodynamics
|December 4, 2024
PubMed
概括

开发了一种新型的多器官芯片 (MOC) 设备,集成肝脏和乳房隔间. 该MOC有助于通过药理动力学-药理动力学 (PK-PD) 建模来评估癌症药物的疗效和安全性,以改善临床前试验.

关键词:
乳腺癌 乳腺癌 乳腺癌有效性 有效性.多个器官在芯片上的多个器官药理动力学是什么 药理动力学药理动力学 药理动力学制药指标 (Pharmacometrics) 是一个指标.安全的安全的安全的安全的安全.

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