心脏代谢指数与女性不孕症之间的关联:一个基于人口的研究
Lingxia Kong1, Xian Ding2, Qian Wang1
1Wuxi School of Medicine, Jiangnan University, Wuxi, China.
PloS one
|December 4, 2024
概括
根据心脏代谢指数 (CMI) 表示的肥胖与美国妇女的不孕症有关. 较高的CMI水平与不孕症风险增加相关,这表明CMI是潜在的查工具.
科学领域:
- 生殖健康 生殖健康
- 代谢健康 代谢健康
- 肥胖问题研究研究
背景情况:
- 肥胖是不孕不育的已知危险因素之一.
- 心脏代谢指数 (CMI) 是一种结合肥胖和血脂的指标,是一种新的肥胖指标.
- CMI与不孕症之间的关联仍未得到充分研究.
研究的目的:
- 调查CMI与美国女性不孕症之间的关联.
- 探索CMI和不孕不育之间的非线性关系和潜在的值效应.
主要方法:
- 利用了2013-2018年国家健康和营养检查调查 (NHANES) 的横截面数据.
- 包括1720名参与者,拥有关于不孕不育和CMI的完整数据.
- 采用多变量逻辑回归,子组分析,平滑曲线拟合和值效应分析.
主要成果:
- 证实了CMI水平和不孕不育发病率之间的正相关性 (OR = 1.12,95% CI: 1.01-1.24).
- 在各个子组分析中保持了显著的关联.
- 值效应分析发现了一个非线性正连接,与CMI 0.93.9的拐点.
结论:
- 在美国女性中,CMI和不孕不育之间存在显著的关系.
- CMI可以作为识别不孕症高风险群体的指标.
- 研究结果可以为改善代谢和生殖健康的临床实践和公共卫生政策提供信息.
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