巴西的炎症性肠病患者样本中的性别差异
Khadija Assis Pascholatto1, Laura Ribeiro Santos1, Thelma Larocca Skare1
1Mackenzie Evangelical School of Medicine of Paraná - Curitiba (PR), Brazil.
Revista da Associacao Medica Brasileira (1992)
|December 4, 2024
概括
患有炎症性肠道疾病 (IBD) 的女性患者,如克罗恩病和性结肠炎更为常见,但只有便秘症状在性别之间有显著差异. 需要进一步的研究来了解基于性别的IBD变异.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
- 流行病学 流行病学
背景情况:
- 炎症性肠道疾病 (IBD),包括克罗恩氏病和性结肠炎,受到环境和免疫学因素的影响.
- 患者的性别可能在IBD的呈现和进展中发挥作用.
研究的目的:
- 调查巴西IBD患者临床形状的基于性别的差异.
- 为了比较男性和女性IBD患者之间的流行病学,症状和治疗特征.
主要方法:
- 从巴西南部的一个大学医院对158名IBD患者 (43名克罗恩病,115名性结肠炎) 的回顾性图表审查.
- 对人口统计数据,临床症状和治疗方案的分析.
主要成果:
- 在克罗恩病 (2.1:1) 和性结肠炎 (1.5:1) 队列中观察到更高的女性对男性的比例.
- 唯一具有统计学意义的差异是女性性结肠炎患者中便秘率增加.
- 在流行病学因素,症状概况或治疗方法方面没有发现其他基于性别的显著差异.
结论:
- 与男性相比,女性占 IBD 患者寻求医疗保健的比例更高.
- 便秘是女性性结肠炎更普遍的症状,但整体临床概况显示性别差异很小.
- 这些发现表明,虽然更多的女性获得IBD护理,但临床表现在两性之间在很大程度上是相似的,便秘是一个显著的例外.
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