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Updated: Jun 5, 2025

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非血红素铁催化剂模仿依赖血红素的氧化酶,以实现高效的化和氧化

Guodong Zhao1,2, Huiling Dong1, Kang Xue1

  • 1School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.

Science advances
|December 4, 2024
PubMed
概括

研究人员开发了一种新的非海姆铁催化剂,模仿天然氧化酶,以实现高效的有机合成. 这种仿生催化剂有效地从过氧化和化中产生反应性HOBr,使各种化反应成为可能.

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In organic synthesis, the formation of products can be altered by changing the reaction conditions. For example, a dibromo addition product is formed when propene is treated with bromine at room temperature. In contrast, propene undergoes allylic substitution in non-polar solvents at high temperatures to give 3-bromopropene. In order to avoid the addition reaction, the bromine concentration must be kept as low as possible throughout the reaction. This can be achieved using N-bromosuccinimide...
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