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Updated: Jun 5, 2025

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线祖利德的结构性毒性关系 (STR) 减轻骨髓抑制和血清毒性毒性

Matin Shaikh1, Harun Patel2

  • 1Division of Computer Aided Drug Design, Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Dhule 425405, Maharashtra, India; Department of Pharmaceutical Chemistry, H. R. Patel Institute of Pharmaceutical Education and Research, Shirpur, Dhule 425405, Maharashtra, India.

Bioorganic & medicinal chemistry
|December 4, 2024
PubMed
概括

研究人员探索了对重要结核病药物Linezolid的修改,以减少诸如骨髓抑制等副作用. 新的类似物显示出对抗多药耐药结核病的更安全,更有效的治疗有希望.

关键词:
线索化物 线索化物骨髓抑制是一种骨髓抑制.血清强毒性毒性 血清强毒性结构性毒性关系是结构性毒性关系.

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