视网母细胞瘤结合蛋白9抑制小鼠的肠道炎症和炎症诱导的瘤发生

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Updated: Jun 5, 2025

Inducible and Reversible Dominant-negative DN Protein Inhibition
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Inducible and Reversible Dominant-negative DN Protein Inhibition

Published on: January 7, 2019

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Kensuke Hamada1, Yuki Nakanishi1, Yu Muta1

  • 1Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Cellular and molecular gastroenterology and hepatology
|December 4, 2024
PubMed
概括

视网母细胞瘤结合蛋白9 (RBBP9) 损失通过激活JAK/STAT1通路而加剧肠道炎症和结肠炎相关癌症. 恢复RBBP9功能抑制了这种途径,为炎症性肠病提供了潜在的治疗策略.

关键词:
大肠炎相关的癌症干扰素信号传输 干扰素信号传输视网母细胞瘤结合蛋白9性结肠炎是一种

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