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相关概念视频

Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

2.6K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.6K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

4.3K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.3K
Obesity01:24

Obesity

416
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
416
The Thyroid Gland01:23

The Thyroid Gland

3.7K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
3.7K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

2.6K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.6K
Metabolic Rate01:25

Metabolic Rate

312
The human body is a powerhouse of energy, with every cell performing numerous functions that require energy. This energy production and consumption is measured by the metabolic rate, which quantifies the total heat generated by all the body's chemical reactions and mechanical work. This measurement helps to determine the rate of kilocalorie (kcal) consumption needed to fuel all ongoing activities.
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence...
312

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相关实验视频

Updated: Jun 14, 2025

Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

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甲状腺功能和人类测量:系统性审查和元分析.

Oscar H Roa Dueñas1, Yanning Xu1, Mohammad Arfan Ikram2

  • 1Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Department of Internal Medicine, Academic Center for thyroid diseases, Erasmus University Medical Center, Rotterdam, the Netherlands.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
|December 4, 2024
PubMed
概括

甲状腺功能会影响人体体重. 较高的甲状腺刺激激素 (TSH) 与增加的BMI相关,而较高的自由甲状腺素 (FT4) 与较低的BMI相关. 需要更多的研究.

关键词:
身体构成 身体组成这是一个元分析.系统性审查 系统性审查甲状腺疾病是一种甲状腺疾病.甲状腺功能 甲状腺功能

更多相关视频

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
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Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

Published on: October 6, 2023

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Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research
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Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research

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相关实验视频

Last Updated: Jun 14, 2025

Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

27.0K
Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
04:14

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

Published on: October 6, 2023

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Author Spotlight: Advancements in 3D Optical Imaging for Comprehensive Body Composition Assessment in Modern Research
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科学领域:

  • 内分泌学 在内分泌学.
  • 代谢健康 代谢健康
  • 公共卫生 公共卫生

背景情况:

  • 患者对甲状腺功能和体重的询问是常见的.
  • 在一般人群中,甲状腺功能与人体测量指标之间的确切关系尚不清楚.

研究的目的:

  • 系统地审查和元分析基于人群的研究和RCT.
  • 为了澄清甲状腺功能 (TSH,FT4) 和人体指标 (BMI,体重) 之间的关联.

主要方法:

  • 在2023年6月28日之前对Embase,Medline和Cochrane中央注册表进行系统的文献搜索.
  • 包括成年人研究,以检查甲状腺功能/疾病作为暴露和人类测量作为结果.
  • 对21项研究进行量化综合的随机效应元分析 (107,734名参与者横截面,22,010人纵横,80个RCT).

主要成果:

  • 截面分析:TSH与BMI正相关 (B=0.21每1mIU/L增加),FT4与BMI负相关 (B=-0.14).
  • 纵向分析:较高的TSH与体重增加有关;较高的FT4与体重减轻有关.
  • 证据质量有限且异质,特别是纵向数据.

结论:

  • 存在一种温和的关联:较高的TSH与较高的BMI/体重相关,较高的FT4与较低的BMI/体重相关.
  • 甲状腺功能和人类测量指标的证据基础很少.
  • 需要高质量的纵向研究来证实这些关联.