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Updated: Jun 16, 2025

Assaying the Kinase Activity of LRRK2 in vitro
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帕金催化域突变的病原性结构基础

Julian P Wagner1, Véronique Sauvé1, Anshu Saran1

  • 1Department of Biochemistry, McGill University, Montreal, Quebec, Canada; Centre de Recherche en Biologie Structurale, McGill University, Montreal, Quebec, Canada.

The Journal of biological chemistry
|December 4, 2024
PubMed
概括

在帕金森的Rcat域中发生的帕金森病突变会损害其活性和泛素结合. 了解这些帕金突变体揭示了线粒和E3酶功能的机制.

关键词:
阿尔法折叠是什么意思阿尔法折叠E3 无处不在的合酶这就是PRKNN.帕金斯是一个停车场.结构生物学结构生物学在任何地方都是无处不在的.

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