第一个三个月的逆转子宫和相关的怀孕结果
Emily R Schneider1, Agata Kantorowska1, Joanna M Clough1
1Department of Obstetrics and Gynecology, NYU Langone Hospital-Long Island, NYU Grossman Long Island School of Medicine, Mineola, New York.
American journal of perinatology
|December 4, 2024
概括
怀孕早期的逆转子宫与第一季度出血的风险较高有关,但不是怀孕流产. 更多患有逆转子宫的患者通过体外受精 (IVF) 怀孕.
科学领域:
- 产科和妇科 产科和妇科
- 生殖医学 生殖医学
- 胎儿超声波检查 胎儿超声波检查
背景情况:
- 在部透光 (NT) 超声波中发现的逆转子宫与怀孕结果之间的关联尚未得到充分证实.
- 了解这些关联对于准确的患者咨询和管理至关重要.
研究的目的:
- 为了研究在NT超声检测中检测到的逆转子宫 (RV) 和第二个三个月的怀孕损失之间的关系.
- 为了探索与逆转子宫相关的其他不良妊娠结果.
主要方法:
- 追溯队列研究,将逆转子宫 (RV) 患者与前转子宫 (AV) 患者进行比较.
- 排除标准包括多胎妊娠,穆勒尔异常和胎儿形.
- 统计分析使用了费舍尔的精确测试,曼-惠特尼测试和多变量逻辑回归.
主要成果:
- 在RV和AV组之间没有观察到第二季度妊娠损失的显著差异 (0%对1.2%,p=0.55).
- 患有逆转子宫的患者在调整种族和试管婴儿后,在第一季度经历阴道出血的可能性是四倍 (16.9%与4.2%,OR=4.1,p=0.0056)).
- 在RV患者中,通过体外受精 (IVF) 怀孕的比例显著更高 (11%对3%,p=0.018).
结论:
- 在第一季度持续的逆转子宫与第一季度阴道出血的风险增加有关.
- 尽管出血风险增加,但怀孕失胎率相似,为患者咨询提供了有价值的信息.
- 在RV组中体外受精受孕的发病率较高,因此需要进一步调查.
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