口腔感染对器官移植的影响:系统性审查
Jenny Olsson1, Sylvia Hunfjörd2, Oscar Braun3
1Department of Oral Pathology, Faculty of Odontology, Malmö University, Malmö, Sweden.
The journal of evidence-based dental practice
|December 4, 2024
概括
移植前的牙科治疗可以减少器官移植接受者的移植后感染. 在实体器官移植之前消除口腔感染的焦点得到了通过将口腔感染与并发症联系在一起的研究结果的支持.
科学领域:
- 移植医学 移植医学
- 口腔健康 口腔健康
- 传染病流行病学 传染病流行病学
背景情况:
- 移植后感染对免疫功能低下的器官接受者构成重大风险.
- 移植前消除口腔感染是减轻移植后发病率的常见做法.
- 移植前牙科治疗对移植结果的必要性和影响仍然不清楚.
研究的目的:
- 系统地审查口腔感染焦点和移植前牙科治疗对固体器官移植后不良事件的影响.
主要方法:
- 对接受实体器官移植的成年患者进行系统审查.
- 在主要数据库中进行电子文献搜索,截至2024年6月.
- 使用叙事方法与偏见风险评估进行数据综合.
主要成果:
- 包括9项包括727名患者的队列研究.
- 在没有牙科治疗的情况下进行肝移植后,人们注意到感染并发症的增加.
- 口腔焦点与脏移植后住院风险有关,但肺移植后感染率较低.
- 没有发现对死亡率或器官排斥有重大影响.
结论:
- 这是关于口腔感染对器官移植的影响的首次系统审查.
- 持续性口腔感染和移植后的传染性并发症之间存在潜在的联系.
- 研究结果支持在实体器官移植之前消除口腔感染焦点.
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