黄酸和肠道微生物组:大脑健康的强大二人组
Soroush Taherkhani1, Parisa Ahmadi2,3, Leila Roozbeh Nasiraie4
1Department of Physiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Critical reviews in food science and nutrition
|December 5, 2024
概括
来自植物的黄类化合物通过与肠道微生物群相互作用,有利于大脑健康. 这种复杂的关系受到饮食和遗传学的影响,影响营养吸收和神经健康.
科学领域:
- 营养神经科学 营养神经科学
- 肠道微生物组研究研究
- 植物化学 植物化学
背景情况:
- 植物性多类植物性多类药物具有健康益处,包括抗衰老,抗癌和抗炎作用.
- 它们的神经保护性与穿越血脑屏障和与神经细胞相互作用有关.
- 叶黄素的吸收受肠道微生物群,年龄,遗传和饮食的影响.
研究的目的:
- 探索黄素,肠道微生物群和神经健康之间的复杂相互作用.
- 调查遗传和环境因素如何影响黄类药物的吸收和有效性.
- 通过肠道微生物群突出类素对大脑健康的积极影响.
主要方法:
- 对有关黄类药物吸收,新陈代谢和神经活性研究的文献综述.
- 对黄和肠道微生物群组成之间的双向关系的分析.
- 检查肠道微生物组在调解黄类物质对中枢神经系统影响中的作用.
主要成果:
- 肠道微生物群通过酶性过程增强了黄酸盐的吸收和生物可用性.
- 黄酸调节肠道微生物群,促进有益的代谢物,如短链脂肪酸 (SCFA).
- 黄类药物会影响神经递质前体的吸收,并通过免疫调节来减少神经炎症.
结论:
- 黄-肠道微生物群轴对神经健康至关重要.
- 遗传和环境因素显著影响着黄胺利用率和大脑益处.
- 调节这一轴为大脑健康和疾病预防提供了一个有前途的治疗策略.
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