印度成年人疫苗接种:快速审查当前状态和实施挑战
Arunaloke Bhattacharyya1, Sheikh Mohammed Shahabuddin2
1Department of Pediatrics, Institute of Child Health, Kolkata, India.
The Indian journal of medical research
|December 5, 2024
概括
印度成年人免疫接种需要提高意识和可获得的疫苗. 关键干预措施包括提高成年人接种疫苗的意识,吸引医疗保健系统,并开发负担得起的,针对特定国家的疫苗,以对抗可预防的疾病.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 免疫学 免疫学 免疫学
背景情况:
- 印度的疫苗接种计划从疫苗接种扩展计划演变为通用免疫计划 (UIP).
- 最近的流行病凸显了成年人,特别是老年人和患有并发病的人对新出现的病原体的脆弱性.
- 本次审查侧重于印度背景下的成人免疫需求.
研究的目的:
- 对印度相关的成人免疫战略进行快速审查.
- 根据现有的文献和指导方针,识别成年人疫苗接种方面的差距和需求.
主要方法:
- 在PubMed,Scopus和Ovid数据库中进行电子搜索.
- 包括印度专业机构的相关共识指南.
- 选了1242个文献记录,其中250篇文章被选中进行综合.
主要成果:
- 有证据支持引入人类乳头瘤病毒 (HPV) 疫苗以预防癌症.
- 流感疫苗 (≤2%) 和乙型肝炎疫苗 (55-64%在HCW中) 的吸收率较低.
- 在成年人群中观察到缺乏防护性免疫力对白喉病,破伤风和麻疹;在宫癌患者中高HPV患病率 (88-98%).
结论:
- 印度的疫苗接种计划需要在成人和医疗保健工作者 (HCW) 中提高意识.
- 卫生保健系统和社区组织的积极参与至关重要.
- 开发和生产负担得起,安全和印度特有的疫苗对于成功至关重要.
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