韩国慢性可代因使用及其对咳相关疾病的影响的全国性研究
Tai Joon An1, Yun-Hee Lee2, Joon-Sung Joh3
1Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Scientific reports
|December 5, 2024
概括
慢性可代因使用与导致咳的潜在疾病,如肺癌和COPD有关. 更安全的使用需要监测,特别是对于老年人和有呼吸系统疾病的人来说.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 胆固醇是一种常见的止咳药,但过度使用会引起安全问题.
- 了解与各种疾病相关的可代因使用模式至关重要.
研究的目的:
- 根据不同的医疗状况,评估可代因使用的状态.
- 为了识别与慢性使用可代因相关的因素.
主要方法:
- 韩国国家健康保险服务样本队列的分析.
- 慢性使用者的定义是那些持续使用抗咳和可代因药物超过60天的人.
- 评估使用模式跨年龄,吸烟状态,包括COPD,喘,GERD和肺癌在内的疾病.
主要成果:
- 在89,289名慢性抗咳使用者中,589人被确定为慢性可代因使用者.
- 慢性使用可代因的人年龄较大,更容易吸烟,多发病率更高.
- 在慢性使用可代因和肺癌 (aOR:6.99),COPD (aOR:2.04),GERD (aOR:1.93) 和慢性咳 (aOR:1.60) 之间发现了积极的相关性.
结论:
- 慢性可代因消费与导致咳的潜在疾病有关.
- 需要加强监测和指导方针,以便更安全地使用可代因.
- 应特别注意老年人和患有慢性呼吸道疾病的个人.
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