丸微石是否与精液参数的降低有关? 一个系统的审查
Hannah G Wilson1, Brian R Birch2,3, Rowland W Rees3
1Faculty of Medicine, University of Southampton, University Road, Southampton, Hampshire, SO17 1BJ, UK. hgw1g20@soton.ac.uk.
Basic and clinical andrology
|December 5, 2024
概括
丸微 (TM) 与精液质量降低有关,特别是精子度降低. 经典TM男性的精子数量比有限TM男性的精子数量低,这表明男性生育能力可能受到影响.
科学领域:
- 生殖性泌尿器科 生殖性泌尿器科
- 安德罗学与人类学
- 医疗成像医学成像
背景情况:
- 丸微症 (TM) 是由丸微化的特征,并与男性不孕症有关.
- 精液分析对于评估TM男性的男性生殖健康至关重要.
研究的目的:
- 系统地比较男性的精液参数与男性的精液参数.
- 为了比较经典TM (≥5个微化) 和有限TM (<5个微化) 之间的精液参数.
- 作为二次结果,分析丸体积和激素水平.
主要方法:
- 按照PRISMA指南进行系统审查,在PROSPERO.上注册.
- 使用纽卡斯尔-太华尺度对所包含研究的质量评估.
- 在Embase,MEDLINE,世界科学和Scopus数据库中搜索了符合条件的研究.
主要成果:
- 包括10项涉及611名患有TM的男性的研究.
- 与对照组相比,患有TM的男性始终表现出较低的精子度.
- 在患有TM的男性中,也观察到精子运动和形态的减少.
- 经典TM与精子度明显低于有限TM有关.
结论:
- 丸微石与精液参数的降低有关,特别是精子度.
- 需要进一步的研究来调查临床结果,如怀孕率.
- 未来的研究应侧重于更大的样本大小,可控变量和先进的精子功能测试.
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