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Updated: Jun 5, 2025

Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells
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翻译后修改 控制 Tau 的相位过渡

Wyatt C Powell1, McKinley Nahum1, Karl Pankratz1

  • 1Department of Chemistry, University of Colorado, Boulder, Boulder, Colorado 80309, United States.

ACS central science
|December 5, 2024
PubMed
概括

在阿尔茨海默病 (AD) 模型中,TAU蛋白的翻译后修饰 (PTM) 通常会阻碍对联螺旋丝 (PHF) 的形成. 酸化始终降低了Tau聚合,而乙化则显示了可变的效应.

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