在更年期前的乳腺磁共振成像中增加了背景辅酶增强
Hidemi Okuma1,2, Amro Masarwah1,2, Aleksandr Istomin2
1Institute of Clinical Medicine, School of Medicine, Clinical Radiology, University of Eastern Finland, P.O. Box 1627, Kuopio Fl 70211, Finland.
European journal of radiology open
|December 5, 2024
概括
与更年期前和更年期后的女性相比,在乳房MRI上,经过更年期后的女性表现出更高的背景辅酶体增强 (BPE). 绝经前期期间的荷尔蒙变化显著影响BPE水平.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 妇女健康 妇女健康
背景情况:
- 乳房MRI上的背景辅酶增强 (BPE) 受各种因素的影响.
- 了解更年期各个阶段的BPE变化对于准确的解释至关重要.
研究的目的:
- 为了比较前期更年期妇女的背景辅酶增强 (BPE) 水平与前期更年期妇女和更年期后妇女使用乳房MRI的水平.
主要方法:
- 从2011年至2015年期间,对562名患者 (年龄为55.8±12.3) 进行了对比增强的动态乳房MRI扫描的回顾性分析.
- 评估的BPE水平,纤维腺组织 (FGT) 量和临床变量.
- 使用了统计方法,包括类间相关系数,斯皮尔曼相关性,曼-惠特尼U测试和皮尔森的千平方测试.
主要成果:
- 对于FGT金额 (0.864) 和BPE水平 (0.840) 的高互读者协议.
- BPE显示了与FGT的微弱正相关性 (ρ=0.271,P<0.001).
- 与更年期前和更年期后组相比,更年期前和更年期前组的BPE在良性和恶性病变方面显著增加.
结论:
- 背景辅酶增强 (BPE) 在绝经前阶段显著增加.
- 随着年龄的增长,BPE表现出非线性下降.
- 绝经前期的荷尔蒙波动对BPE水平产生重大影响,可能比以前认识的更大.
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