骨肌肉蛋白质组在年轻的APOE3和APOE4向替代小鼠之间以性别依赖的方式不同

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Updated: May 13, 2026

Skeletal Muscle Gender Dimorphism from Proteomics
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Published on: December 14, 2011

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Chelsea N Johnson1,2, Colton R Lysaker2,3, Colin S McCoin1,4

  • 1Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, MO, United States.

Frontiers in aging neuroscience
|December 5, 2024
PubMed
概括

阿波利波蛋白E4 (APOE4) 基因对年轻小鼠的骨肌肉线粒体产生影响. 这种阿尔茨海默病的遗传风险因素以性别依赖的方式改变线粒体基因表达,表明早期的肌肉参与.

关键词:
在APOE4OE4中使用.阿尔茨海默病的疾病阿尔茨海默病的疾病.鼠标 鼠标 鼠标 鼠标线粒体中的线粒体.蛋白质组学 蛋白质组学这是骨肌肉的骨架肌肉.

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