解决全球阿片类药物危机:将遗传成风险评估与个性化多巴胺基因平稳疗法和意识整合疗法的结合
Foojan Zeine1,2, Nicole Jafari3,4, David Baron5
1Awareness Integration Institute, San Clemente, USA.
概括
全球阿片类药物危机需要新的治疗策略,超越传统方法. 本综述提出了一个模式转变,重点关注多巴胺平衡和个性化成风险评估,以改善结果.
科学领域:
- 神经科学和药理学 神经科学和药理学
- 成 药物 药物 药物 药物
- 遗传学和表观遗传学
背景情况:
- 阿片类药物危机在全球范围内升级,压倒了传统治疗疗效.
- 现有的降低危害策略,如阿片类药物替代疗法 (OST),在制死亡率上升方面取得了有限的成功.
- 药物使用障碍 (SUD) 影响着数百万人,过量服用死亡人数显著增加,主要是由阿片类药物驱动的.
研究的目的:
- 对导致全球阿片类药物危机的多因素决定因素进行深入审查.
- 批判性地评估当前的治疗模式,并倡导修订护理标准.
- 探索针对阿片类药物成的神经生物学基础的新型治疗方法.
主要方法:
- 一个叙述性的评论和意见文章.
- 在PsychINFO,PubMed,Google Scholar和Web of Science进行了文献搜索.
- 确定了专注于阿片类药物危机,机制,遗传学,神经药理学和临床治疗/预防的文章.
主要成果:
- 美国与阿片类药物相关的过量死亡人数继续上升,每年超过106,699人,预计到2025年将达到165,000人.
- 2020年,美国超过4000万个人经历了物质使用障碍 (SUD).
- 临时数据显示,2021年过量服用死亡人数增加了15%,阿片类药物涉及约80,816人死亡.
结论:
- 倡导重新评估目前对阿片类药物成治疗的"标准护理".
- 建议一种新的方法,通过非成的替代品和遗传风险评估 (遗传上风险严重程度 - GARS) 强调多巴胺稳态.
- 整合综合疗法,如意识整合疗法 (AIT),解决心理,精神和社会因素.
关键词:
意识整合疗法意识整合疗法认知行为疗法是一种认知行为疗法.车库 车库 车库 车库在H波疗法中,使用H波.KB22020 在此之前,KB220药物辅助疗法是药物辅助疗法.正念是一种正念.片危机 片危机 片危机重复性横性磁性刺激的重复性磁性刺激奖励缺陷综合征是一种奖励缺陷综合征.合成阿片类药物合成阿片类药物创伤疗法的治疗方法更多相关视频
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