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在肺高血压中,THBS1调解缺氧驱动的EndMT

Bingming Peng1,2,3, Yingzhen Zhou1,2,3, Xingmeng Fu1,2,3

  • 1Department of Respiratory, Thoracic and Cardiac Surgery, Cardiovascular Medicine Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders Chongqing China.

Pulmonary circulation
|December 5, 2024
PubMed
概括

血栓素1 (THBS1) 在肺高血压 (PH) 中驱动缺氧诱导的内皮细胞转化为介质细胞转化 (EndMT). 抑制THBS1逆转了EndMT,为先天性心脏病患者提供了对PH病理生理学的新见解.

关键词:
最终的MT 结束的MT在THBS1中,THBS1是THBS1.缺氧 缺氧是指缺氧的情况.肺高血压是一种肺高血压.肺血管重塑 肺血管重塑

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