富含proline-glutamine分离因子的细胞质聚合物破坏核细胞质运输,并诱导持久的压力颗粒

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Methods to Classify Cytoplasmic Foci as Mammalian Stress Granules
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Methods to Classify Cytoplasmic Foci as Mammalian Stress Granules

Published on: May 12, 2017

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Zicong Huang1, Hanbin Zhang2, Chuyu Huang3

  • 1Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.

Journal of cellular and molecular medicine
|December 5, 2024
PubMed
概括

错位的SFPQ蛋白质形成细胞质聚合物,捕获不成熟的RNA并导致持续的压力颗粒 (SG). 这种RNA结合蛋白的功能障碍影响RNA处理和核细胞质运输,揭示了它的病理作用.

关键词:
RNA代谢的RNA代谢过程在SFPQQ中,SFPQ是最重要的.细胞质聚合物的细胞质聚合物核细胞质体运输是核细胞质体运输.应力颗粒的压力颗粒

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