运动神经元疾病和中枢神经系统尾道病:临床-放射学相关性和诊断方法
Amit B Desai1, Amit Agarwal1, Alaa S Mohamed1
1From the Departments of Radiology (A.B.D., A.A., E.H.M., A.A.B., V.G.) and Neurology (A.S.M., K.H.M., S.L.C.), Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224; Department of Neurology, Mayo Clinic, Rochester, MN (N.K., E.S., E.P.F.); and Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy (E.S.).
概括
中枢神经系统白质通道的损伤,称为通道病,可以损害运动功能. 这篇综述详细介绍了动力神经元疾病的成像发现,如肌缩侧面硬化症 (ALS) 和二级皮质脊柱状脊髓病变.
科学领域:
- 神经成像是一种神经成像.
- 神经学 神经学
- 病理学 病理学 病理学
背景情况:
- 白质道对于感觉和运动功能至关重要.
- 轨道病变,或损害这些通道,可以导致感觉或运动障碍.
- 运动神经元疾病,如肌缩侧面硬化症 (ALS),会影响运动神经元.
研究的目的:
- 为了审查运动神经元疾病和皮质脊髓叶道病的特征性成像特征.
- 突出结合临床,放射学和实验室诊断发现的重要性.
主要方法:
- 综述各种运动神经元疾病和二次肌肉病的MRI发现.
- 描述特征性成像标志,包括T2超强度和"机动带"标志.
主要成果:
- 肌缩侧面硬化症 (ALS) 在皮质脊髓管和"动力带"信号中显示T2高强度.
- 脊柱肌肉缩呈现出前角和肌肉缩.
- 二次性皮质脊髓轨道病变在MRI上表现出T2高强度病变.
结论:
- 清晰的成像功能有助于诊断运动神经元疾病和轨道病变.
- 综合诊断方法对于区分这些疾病至关重要.
- 磁力共振成像在识别影响运动功能的白质通道异常方面发挥着关键作用.
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