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Updated: Jun 5, 2025

Mitigation of Blood Borne Cell Attachment to Metal Implants through CD47-Derived Peptide Immobilization
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Mitigation of Blood Borne Cell Attachment to Metal Implants through CD47-Derived Peptide Immobilization

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用于植入物应用的SiRNA修饰的聚乙基表面增强的细菌静止和骨整合性质

Zhen Liu1, Libin Yang2, Yazhuo Ni3

  • 1Department of Stomatology, Airforce Medical Center PLA, Air Force Medical University, Beijing, People's Republic of China.

PloS one
|December 5, 2024
PubMed
概括

这项研究修改了具有RNA干扰 (RNAi) 和酸涂层的聚乙基 (PEEK) 植入物. 增强的PEEK植入物显示出更好的骨整合和减少细菌感染,以更好的骨替代物应用.

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Bacterial Signaling01:30

Bacterial Signaling

Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
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