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人类iPSC衍生的髓化器官和球状细胞用于研究克拉贝病

Lisa Marie P Evans1, Joseph Gawron1, Fraser J Sim2

  • 1Departments of Biochemistry and Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, United States of America.

PloS one
|December 5, 2024
PubMed
概括

克拉贝病 (Kd) 涉及由于银糖胺酶缺乏症而导致的髓损失. 患者衍生的有机体揭示了早期的髓化缺陷,而微质细胞模型揭示了球状细胞形成机制.

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