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Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
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工程合成抑制T细胞执行局部向的免疫保护程序

Nishith R Reddy1,2, Hasna Maachi3, Yini Xiao1,2,3

  • 1UCSF Cell Design Institute, University of California, San Francisco, San Francisco, CA, USA.

Science (New York, N.Y.)
|December 5, 2024
PubMed
概括

研究人员设计T细胞以精确地抑制本地免疫反应. 这些合成抑制T细胞提供有针对性的免疫调节,保护组织免受攻击而不会引起系统性影响,并可能治疗各种与免疫相关的疾病.

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