通过身体活动调节肠道微生物群在肥胖个体-一个系统性审查
Javiera Cancino Ramírez1,2, Luis González Rojas3, Fabien Magne2
1Clínica Universidad de los Andes, Unidad de Medicina Física y Rehabilitación, Chile.
概括
身体活动和炼对超重/肥胖个体的肠道微生物群组成有积极的影响. 适度到剧烈的活动特别增强有益细菌,影响肥胖症治疗策略.
科学领域:
- 微生物学 微生物学
- 运动生理学 运动生理学
- 肥胖问题研究研究
背景情况:
- 超重/肥胖 (OW/OB) 与肠道失调,胃肠机动性变化和久坐不动行为有关,有助于代谢和炎症问题.
- 肠道微生物群在宿主新陈代谢和炎症中起着至关重要的作用,对肥胖的发展和管理有潜在的影响.
研究的目的:
- 系统地审查有关身体活动和炼对肠道微生物群组成和多样性的影响的证据,对OW/OB.
- 用既有偏见风险评估工具评估现有研究的质量.
主要方法:
- 按照PRISMA指南对MEDLINE,EMBASE,EBSCO和Scopus数据库进行系统的文献搜索.
- 包括11项研究 (476名OW/OB,382名正常体重的个体),包括RCT,非RCT和横截面研究.
- 使用RoB 2,ROBINS-I和JBI批判性评估工具进行偏差风险评估.
主要成果:
- 没有明确的证据表明OW/OB个体的肠道微生物群多样性减少.
- 运动干预措施没有显著改变α多样性,但根据肥胖状况影响了β多样性.
- 适度至剧烈的体力活动与肠道微生物群组成和短链脂肪酸 (SCFA) 生产细菌有积极的关联.
结论:
- 肠道微生物群的组成受到OW/OB个体体体育活动水平的影响.
- 身体活动,特别是中度到强烈的强度,可以促进更健康的肠道微生物特征.
- 通过身体活动调节肠道微生物群是个性化肥胖治疗的潜在策略.
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