杀菌剂,抗生素和抗体在土壤-生菜系统中的迁移
Chenyu Huang1, Minrong Cui1, Tongxin Li1
1Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests, Ministry of Agriculture and Rural Affairs, Institute of Pesticide and Environmental Toxicology, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, China.
Journal of hazardous materials
|December 5, 2024
概括
杀菌剂和抗生素加速了抗生素耐药性基因 (ARG) 从土壤传播到生菜. 这增加了细菌的多药耐药性,对食品安全和作物健康构成风险.
科学领域:
- 环境微生物学环境微生物学
- 农业科学 农业科学
- 食品安全 食品安全
背景情况:
- 抗生素耐药性基因 (ARG) 对全球农业构成重大威胁.
- 了解ARG的传播,特别是在农药和抗生素的联合暴露下,至关重要.
研究的目的:
- 在杀菌剂和抗生素暴露下,研究土壤-生菜系统中的ARG传播途径.
- 评估这些农业化学品对多种抗生素耐药性发展的影响.
主要方法:
- 使用了超基因组装和包装.
- 对暴露于杀菌剂 (卡本达齐姆,皮拉克洛斯特罗宾) 和抗生素 (chlortetracycline, ciprofloxacin) 的土壤-生菜系统进行了分析.
主要成果:
- 农业化学品促进了ARG从土壤转移到生菜.
- 多种抗生素的耐药性增加,特别是对硫胺,氨基糖化物,金和四环素的耐药性增加.
- 等离子体是横向基因转移的关键,使致病细菌能够获得耐药性.
结论:
- 杀菌剂和抗生素驱动土壤-生菜系统中的ARG迁移.
- 这降低了农产品的安全性和质量.
- 确定了对作物健康和食品安全的潜在风险.
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