"KRAS":.

Adrienne D Cox1,2,3, Channing J Der1,3

  • 1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA; cjder@med.unc.edu adrienne_cox@med.unc.edu.

Genes & development
|December 5, 2024
PubMed
概括

针对肺癌,结直肠癌和胰腺癌中常见的KRAS突变,花了数十年的时间. 新的直接RAS抑制剂和组合疗法正在出现,以克服耐药性并改善对KRAS突变癌症的治疗.

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