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克罗恩病儿童磁共振肠道学预后价值:一个多中心,多读者研究

Anastasiia Romanchuk¹, Clarissa Valle², Arianna Ghirardi³

¹Department of Pediatrics, Pediatric Infectious Diseases, Immunology and Allergology, Shupyk National Healthcare University of Ukraine, Ukraine; Pediatric Hepatology Gastroenterology and Transplantation Unit, ASST Papa Giovanni XXIII, Bergamo, Italy.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

|December 5, 2024

概括

儿科炎症克罗恩病MRE指数 (PICMI) 可靠地评估了儿科克罗恩病的活动. 诊断时较高的PICMI得分预示着更需要生物疗法来实现缓解.

科学领域:

儿科胃肠病学儿科胃肠病学
放射学放射学是一门学科.
炎症性肠道疾病炎症性肠病

背景情况:

儿科炎症克罗恩病MRE指数 (PICMI) 评估了儿科克罗恩病 (CD) 中的肠道炎症.
评估PICMI对疾病过程的预测价值及其读者间可靠性至关重要.

研究的目的:

为了确定诊断时的PICMI得分是否可以预测小儿克罗恩病的长期病程.
为了评估PICMI评分的读者间协议.

主要方法:

儿童CD患者的回顾性招募,至少进行一年的随访.
放射科医生在诊断时计算PICMI得分.
分析了PICMI,儿科克罗恩病活动指数 (PCDAI) 和CD内镜严重性指数 (CDEIS) 之间的相关性.

主要成果:

分析了68名患有CD的儿童;PICMI得分与诊断时的PCDAI有显著的相关性.
较高的初始PICMI分数与1,3年和5年的生物治疗引入需求增加有关.
不同的PICMI严重程度组的无类固醇缓解率是可比的.

结论:

皮克米评分是一个可靠和可重复的工具,用于评估儿童克罗恩病的疾病活性.
诊断时PICMI得分较高的儿童需要更密集的治疗,包括生物药物,以达到类似的缓解率.

关键词:

生物治疗方法生物治疗方法孩子孩子孩子孩子疾病活动疾病活动炎症性肠病是一种炎症性肠病.肠道炎症是一种肠道炎症.

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