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Updated: Jun 5, 2025

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
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Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay

Published on: March 10, 2020

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肌蛋白VI驱动了GPCRs的独立内部化和信号的停止

Nishaben M Patel1, Léa Ripoll2, Chloe J Peach3,4

  • 1Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, USA.

Nature communications
|December 5, 2024
PubMed
概括

对于G蛋白结合受体 (GPCR) 内化的一种新途径涉及与β-arrestins独立的myosin VI. 这一发现揭示了myosin VI的存在.

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