相关实验视频

Updated: May 5, 2026

Direct Tracheal Instillation of Solutes into Mouse Lung
04:50

Direct Tracheal Instillation of Solutes into Mouse Lung

Published on: August 29, 2010

29.1K

在对小鼠的毒性研究中,常用车辆的反复内内灌注效应

In-Hyeon Kim1,2, Je-Hein Kim1, Se-Woong Park1,2

  • 1Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeongeup, Republic of Korea.

Scientific reports
|December 5, 2024
PubMed
概括

内灌注 (ITI) 毒性研究需要仔细选择载体. 这项研究发现,玉米油,DMSO和乙醇等常见载体可以在小鼠中引起呼吸道毒性,影响研究设计.

关键词:
背景数据 背景数据纳米材料是一种纳米材料.监管毒理学 监管毒理学呼吸道暴露 呼吸道暴露

更多相关视频

An Improved Method for Rapid Intubation of the Trachea in Mice08:46

An Improved Method for Rapid Intubation of the Trachea in Mice

Published on: February 22, 2016

25.1K
Noninvasive Intratracheal Lipopolysaccharide Instillation in Mice04:10

Noninvasive Intratracheal Lipopolysaccharide Instillation in Mice

Published on: March 31, 2023

4.3K

相关概念视频

Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
204