在高血压患者中,继续运动习惯三年和内皮功能之间的关系
Takayuki Yamaji1,2, Farina Mohamad Yusoff2, Shinji Kishimoto2
1Center for Radiation Disaster Medical Science, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
概括
保持定期的运动习惯可以显著改善高血压患者的内皮功能. 即使是低强度的运动也可以改善血管健康,这表明运动对于控制高血压至关重要.
科学领域:
- 心血管医学 心血管医学
- 运动生理学 运动生理学
- 高血压研究 高血压研究
背景情况:
- 内皮功能障碍是高血压的一个关键因素.
- 众所周知,定期运动有益于心血管健康.
- 持续炼习惯对高血压患者内皮功能的长期影响需要进一步阐明.
研究的目的:
- 研究高血压患者长期持续炼习惯与内皮功能之间的关系.
- 用流介导血管扩张 (FMD) 来评估内皮功能.
主要方法:
- 一个多中心的回顾性观察性研究,涉及639名高血压患者.
- 根据3年的随访,被试被分为定期炼和非定期炼 (对照) 组.
- 通过流介导血管扩张 (FMD) 来评估内皮功能.
主要成果:
- 群体之间没有口病的显著基线差异.
- 与对照组相比,定期炼组的口和口腔炎的增加明显更大 (p=0.008).
- 调整后的分析显示,在经常炼组中,口炎增加的几率比率更高 (OR:1.59,p=0.006),即使在较低的炼强度 (<20 METs·hour/week) 中也观察到好处.
结论:
- 定期炼与高血压患者内皮功能改善有关.
- 持续的炼习惯,即使是中等强度的炼习惯,也有助于改善这种人群的血管健康.
- 鼓励定期体育活动可能是管理高血压及其相关内皮功能障碍的有价值策略.
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