基于多糖的癌症治疗药物输送系统的最新进展:综合性审查
Chou-Yi Hsu1,2, Omer Qutaiba B Allela3, Ali M Hussein4
1Department of Pharmacy, Chia Nan University of Pharmacy and Science, Tainan City, Taiwan.
Artificial cells, nanomedicine, and biotechnology
|December 5, 2024
概括
基于多糖的药物递送系统 (DDS) 为传统的癌症疗法提供了一个有希望的替代方案. 这些天然生物材料提供有效和有针对性的治疗药物,克服当前治疗方法的局限性.
科学领域:
- 生物材料科学 生物材料科学
- 制药科学 制药科学
- 在瘤学瘤学.
背景情况:
- 癌症是一个重大的全球健康挑战,发病率和死亡率很高.
- 传统的癌症治疗,如化疗,具有显著的缺点,包括非特异性,转移和高成本.
- 对于创新的癌症抑制技术有着至关重要的需求.
研究的目的:
- 审查基于多糖的药物输送系统 (DDS) 在制药科学和癌症治疗中的实际应用.
- 突出多糖类作为癌症治疗的可靠药物载体.
- 讨论基于多糖的DDS相对于传统方法的优势.
主要方法:
- 关于基于多糖的药物输送系统的科学文献的审查.
- 对各种多糖的特性和应用的分析 (奇托桑,阿尔基纳酸盐,德克斯,氨酸,循环德克斯,丁).
- 从自然资源 (植物,海洋,微生物) 中提取的多糖的评估.
主要成果:
- 多糖体对药物输送具有有利的特性,包括易于修改,水性,血清稳定性,生物相容性和生物降解性.
- 这些生物聚合物使刺激反应和持续的药物释放成为可能,从而提高治疗疗效.
- 基于多糖的DDS显示出作为向癌症治疗的可靠载体的巨大潜力.
结论:
- 基于多糖的DDS代表了有效抑制癌症的突破性技术.
- 它们的固有特性使得它们成为开发先进的癌症治疗药物的优秀候选人.
- 对基于多糖的DDS进行进一步的研究对于推进制药科学和改善癌症治疗结果至关重要.
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