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Updated: Jun 5, 2025

A "Dual-Addition" Calcium Fluorescence Assay for the High-Throughput Screening of Recombinant G Protein-Coupled Receptors
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合理复合选择的模拟可访问性得分 (AAscore)

Takato Ue1, Akinori Sato1,2, Tomoyuki Miyao1,2

  • 1Graduate School of Science and Technology, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma, Nara630-0192, Japan.

Journal of chemical information and modeling
|December 6, 2024
PubMed
概括

开发了一个新的模拟可访问性评分 (AAscore),使用in silico模型来预测虚拟模拟器. 这一分数有助于在药物发现中优先考虑化合物,但与实验合成的类似物显示出有限的相关性.

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