耗积分和痛风:从NHANES数据的见解
Xu Cao1, Haixia Feng2, Huijie Wang1
1Department of Endoscopy, Shijiazhuang Traditional Chinese Medicine Hospital, Shijiazhuang, China.
Frontiers in nutrition
|December 6, 2024
概括
用耗积分 (MDS) 衡量的缺乏与美国成年人中痛风风险更高有关. 饮食摄入量没有影响这种关联,突出显示了全身状况的重要性.
科学领域:
- 营养科学 营养科学
- 代谢障碍 代谢障碍 代谢障碍
- 流行病学 流行病学
背景情况:
- 痛风是一种与高尿血症相关的代谢障碍.
- 血清含量与尿酸水平相反相关.
- 饮食中的摄入量可能会降低高尿血症风险,但全身状况 (MDS) 在痛风中的作用尚不清楚.
研究的目的:
- 调查耗评分 (MDS) 与痛风风险之间的关联.
- 探索饮食摄入量是否会改变MDS和痛风之间的关系.
主要方法:
- 来自国家健康和营养检查调查 (2007-2016) 的18039名美国成年人的分析.
- 使用MDS评估缺乏症.
- 权重多变量后勤回归和子组分析,以评估MDS-痛风相关性,考虑饮食摄入量.
主要成果:
- 在研究人口中,痛风的患病率为4.7%.
- 在对混因素进行调整后,在MDS和痛风风险之间发现了显著的正相关性.
- 与MDS为0的人相比,MDS为2或≥3的个体患上痛风的几率明显更高 (OR分别为1.86和2.17).
- 饮食中的摄入量没有缓解MDS和痛风风险之间的关联.
结论:
- 系统性缺乏症,以较高的MDS表示,与美国成年人中痛风风险增加有关.
- 饮食中的摄入量似乎没有影响全身状况和痛风风险之间的关系.
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