由于COVID-19后综合征引起的皮肤学并发症:系统性审查
Beatriz Arely Cayón Figueroa1, Wendy Mendoza Rojas2, Daniel Tiburcio Jiménez3
1Division of Internal Medicine, Hospital Regional ISSSTE León, León 37520, Guanajuato, Mexico.
Medicine international
|December 6, 2024
概括
在近20%的患者中,COVID-19后综合征可能会导致皮肤问题,如皮疹和脱发. 还注意到自身免疫性皮肤病变,特别是在严重病例和女性中,这表明需要新的治疗方法.
科学领域:
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
背景情况:
- 后COVID-19综合征经常表现为皮肤学表现.
- 这些症状与高炎症和CD8+T细胞放松调节有关.
- 目前的治疗依赖于症状,因为缺乏特定疗法.
研究的目的:
- 系统地审查和描述与后COVID-19综合征相关的皮肤症状的类型和患病率.
- 为了确定这些皮肤病的潜在自身免疫成分和风险因素.
- 为突出后COVID-19皮肤表现的新兴治疗需求.
主要方法:
- 使用PICO策略进行系统审查.
- 在PubMed,谷歌学者,Embase和Scopus数据库中进行了搜索.
- 包括44项专注于"COVID后和皮肤症状"的研究.
主要成果:
- 皮疹是最常见的非特异性症状 (高达27.4%).
- 脱发症 (脱发) 影响高达50%的受试者.
- 确定了自身免疫性皮肤病变和表皮性自身抗体 (高达41%),在女性和严重的COVID-19病例中更为普遍.
结论:
- 后COVID-19综合征导致显著的皮肤学变化,特别是影响头发健康,特别是在女性.
- 自免疫性皮肤病变的存在代表了一个新兴的治疗挑战.
- 需要进一步的研究来理解和管理这些后病毒性皮肤病症.
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