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Updated: May 11, 2026

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CBP/p300 lysine acetyltransferases抑制了潜伏感染的T细胞中的HIV-1表达

Riley M Horvath1, Ivan Sadowski1

  • 1Department of Biochemistry and Molecular Biology, Molecular Epigenetics Group, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.

iScience
|December 6, 2024
PubMed
概括

基斯脱乙酶抑制剂 (HDACi) 能够重新激活HIV-1. 令人惊的是,CBP/p300乙转移酶抑制剂也可以逆转HIV-1潜伏期,这表明蛋白质乙化会影响病毒的表达.

关键词:
生物科学 生物科学免疫学 免疫学 免疫学

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