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Updated: Jun 11, 2026

Formulation of Diblock Polymeric Nanoparticles through Nanoprecipitation Technique
06:47

Formulation of Diblock Polymeric Nanoparticles through Nanoprecipitation Technique

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基于设计质量 (QbD) 的RP-HPLC方法的开发和验证,用于聚合物纳米颗粒中的布塞林酸盐:释放研究

Rashmi S Tambare1, Sadhana R Shahi2, Vishal C Gurumukhi3

  • 1Department of Pharmaceutics, Shreeyash Institute of Pharmaceutical Education and Research, Aurangabad, 431010, Maharashtra, India.

Heliyon
|December 6, 2024
PubMed
概括

开发了一种使用设计质量的新分析方法,用于布塞雷林酸盐,一种降低雌激素的乳腺癌药物. 经过验证的RP-HPLC方法准确地量化了聚合物纳米颗粒中的布塞雷林酸盐.

关键词:
BA-加载的聚合物纳米粒子布塞雷林乙酸是一种染色体学 染色体学 是一种染色学.从设计开始的质量.验证 验证 验证 验证

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A Workflow for Lipid Nanoparticle LNP Formulation Optimization using Designed Mixture-Process Experiments and Self-Validated Ensemble Models SVEM13:54

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Changes in polymorphic forms can significantly influence the bioavailability of poorly soluble drugs. Although the FDA defines pharmaceutical equivalence based on having the same active ingredient, dosage form, and route of administration, it does not automatically disqualify products with different polymorphic forms. This means two products with different polymorphs can still be deemed pharmaceutically equivalent. However, polymorphic differences can affect properties like wettability,...
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