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Updated: Jun 5, 2025

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
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A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

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识别编码的胺寡合物的序列选择性拉下,使用对固体支物的共价捕获

Luis Escobar1, Daniel Sun1, Mohit Dhiman1

  • 1Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK. herchelsmith.orgchem@ch.cam.ac.uk.

Chemical communications (Cambridge, England)
|December 6, 2024
PubMed
概括

研究人员开发了一种方法,使用目标分子捕获特定的胺寡合体. 这种技术可以通过序列选择性拉下来发现功能识别编码的胺寡合体 (REMO).

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相关概念视频

Maxam-Gilbert Sequencing01:05

Maxam-Gilbert Sequencing

In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
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