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Updated: Jun 4, 2026

PAR-CliP - A Method to Identify Transcriptome-wide the Binding Sites of RNA Binding Proteins
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在大规模RNA结合特征的帮助下,对G--RNA复合体进行晶体分析

Ryosuke Nagasawa1,2, Kazumitsu Onizuka1,2,3, Karen Kawamura4

  • 1Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Miyagi 980-8577, Japan. onizuka@tohoku.ac.jp.

Chemical communications (Cambridge, England)
|December 6, 2024
PubMed
概括

我们确定了与前微型RNA-125a结合的G的X射线晶体结构. 该结构显示G与RNA循环中的三个关氨基基形成强烈的相互作用.

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相关概念视频

Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...