1型布鲁加达模式的患病率和发生率:梅奥诊所30年的经验
Pattara Rattanawong1, Carolyn Mead-Harvey2, Olubadewa A Fatunde1
1Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ.
Mayo Clinic proceedings
|December 6, 2024
概括
1型布鲁加达模式的发病率在过去30年里有所增加,其患病率高于美国以前报告的. 这种布鲁加达模式在黑人和西班牙裔人口中比人们怀疑的更为常见.
科学领域:
- 心脏病学 心脏病学
- 遗传学 是一个遗传学.
- 流行病学 流行病学
背景情况:
- 布鲁加达模式是一种心电图 (ECG) 发现,与心脏突然死亡风险增加有关.
- 之前关于布鲁加达模式发生率和流行率的研究有所不同.
- 了解时间趋势和人口变化对于风险分层至关重要.
研究的目的:
- 为了确定1型布鲁加达模式的发病率和流行率.
- 为了分析梅奥诊所三十年来的趋势.
- 调查布鲁加达模式发病率中的种族和民族差异.
主要方法:
- 从2,304,809名患者 (1992-2021) 获得的5,381,186个心电图的回顾性审查.
- 使用系统的关键词搜索识别1型布鲁加达模式.
- 根据十年的发病率和种族群体之间的发病率比率 (IRR) 的计算.
主要成果:
- 1型布鲁加达模式的发病率在30年内显著增加.
- 总体患病率 (2010-2021) 为每10万人/年10.094人.
- 与非西班牙裔白人患者相比,西班牙裔白人 (3倍) 和黑人 (1.5倍) 患者的发病率更高.
结论:
- 在过去的30年中,1型布鲁加达模式的发病率有所上升.
- 美国的患病率高于此前估计的.
- 1型布鲁加达模式在黑人和西班牙裔人口中比以前认可的更为常见.
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