联合学习用于增强剂量-体积参数预测,使用分散的数据
Jiahan Zhang1, Yang Lei1, Junyi Xia1
1Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Medical physics
|December 6, 2024
概括
联合学习 (FL) 通过训练使用分布式,私有数据的中央模型,使精确的放射瘤规划成为可能. 这种方法与没有共享数据的集中模型性能相匹配,克服了采用障碍.
科学领域:
- 辐射瘤学 辐射瘤学
- 机器学习 机器学习
- 医疗数据 隐私 医疗数据 隐私
背景情况:
- 在放射性瘤学中,基于知识的规划受到数据稀缺和医疗数据共享的挑战的限制.
- 这些局限性阻碍了先进规划技术的广泛采用.
研究的目的:
- 评估联合学习 (FL) 的可行性,以克服辐射瘤学的数据共享限制.
- 开发一种保护隐私的方法,用于训练使用分布式数据集的集中模型.
主要方法:
- 一个渐变增强模型使用273个前列腺癌计划预测了膀和直肠剂量-体积指标 (V30Gy,V35Gy,V40Gy).
- 联邦平均算法从10个模拟诊所子集中汇总了模型重量.
- 用不同数量的站点和不平衡的数据分布来测试模型的稳定性.
主要成果:
- FL模型的平均绝对误差 (MAE) 为4.7%±2.9%,明显低于单个模型 (6.5%±4.9%) 和可与集中模型 (4.4%±2.8%) 相比.
- FL模型在不同数量的子集 (5-30) 中显示出稳定性,并且在不平衡的数据集上表现良好.
- 在膀和直肠指标方面,FL方法的表现优于单个模型的36.7%.
结论:
- 联合学习为放射性瘤学中的基于知识的规划提供了一个可行的解决方案,在不集中敏感患者数据的情况下提高了预测准确性.
- 即使在本地站点数据稀缺的情况下,FL模型也保持了高性能,比单独训练的模型更强大.
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