生物炭通过通过持久性自由基介导的干扰定数传感来降低土壤中人类细菌病原体的风险
Yangjuan Cheng1, Kun Lu1, Zaiming Chen1
1Zhejiang Provincial Key Laboratory of Solid Waste Treatment and Recycling & International Science and Technology Cooperation Platform for Low-Carbon Recycling of Waste and Green Development, School of Environmental Science and Engineering, Zhejiang Gongshang University, Hangzhou 310012, China.
Environmental science & technology
|December 6, 2024
概括
米的生物炭有效地减少了人类的细菌病原体及其有害影响,因为它破坏了定数感应. 这种生物炭显示出对更安全的土壤修复技术的希望.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 土壤科学 土壤科学
背景情况:
- 生物炭可以减少土壤中的抗生素耐药性基因 (ARG) 和移动遗传元素 (MGE).
- 生物炭对人类细菌病原体 (HBPs) 和毒性因子基因 (VFGs) 的影响还未得到充分研究.
研究的目的:
- 调查米 (RS) 和松木 (PW) 生物炭对HBP丰度和致病性的影响.
- 阐明生物炭对HBPs的影响背后的机制.
主要方法:
- 在350°C和700°C下对RS和PW进行热解,以制造生物炭.
- 用不同生物炭处理的土壤中HBPs和VFGs的量化.
- 对持久性自由基 (PFR) 和N-基-l-同素乳 (C4-HSL) 降解的分析.
主要成果:
- 与PW生物炭相比,RS生物炭显著降低了HBP的丰度 (6.3-40.1%) 和致病性 (8.2-10.1%的VFG减少).
- RS生物炭含有更多的PFR,这些PFR降解了C4-HSL,这是定数感应 (QS) 中的关键分子.
- 通过RS生物炭破坏QS,阻碍了HBP的传播,并降低了毒性.
结论:
- 通过干扰QS机制,RS生物炭有效降低HBP的丰富性和病原性.
- 可以开发基于生物炭的土壤整治技术,以减轻与HBPs相关的风险.
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