在不受管制的药物供应中与伤口相关的毒剂:来自全州药物检查计划的证据
Emily M Martin1, Kristin E Schneider1, Edward Sisco2
1Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, 1812 Ashland Avenue, 3rd Floor, Baltimore, MD 21205, USA.
The International journal on drug policy
|December 6, 2024
概括
马里兰州的药物供应中存在像西拉这样的与伤口相关的药物,随着时间的推移,西拉的含量会减少. 对这些物质的监测对于公共卫生和减少危害的战略至关重要.
科学领域:
- 公共卫生 公共卫生
- 法医化学 法医化学
- 药品市场分析 药品市场分析
背景情况:
- 不受监管的药物市场日益波动,人们越来越担心除了芬太尼之外的伪造剂.
- 与伤口相关的物质越来越多地被记录下来,但随着时间的推移,它们在药物供应中的流行程度仍未得到充分研究.
- 这项研究调查了马里兰州药物供应中关键的伤口相关药物的存在.
研究的目的:
- 为了确定马里兰州不受管制的药物供应中西拉,莱瓦米索尔和梅德托米丁的流行率.
- 分析这些剂与其他物质的同时出现.
- 为了追踪西拉流行的时间和地理趋势.
主要方法:
- 通过马里兰州的药物快速分析 (RAD) 计划,在2021年10月至2023年10月期间收集的2,210个药物样本的分析.
- 利用了注射器服务计划和国家标准与技术研究所分析的数据.
- 用人患病率计算和千平方显著性用于同时发生和时间趋势分析.
主要成果:
- 在33.4%的样本中检测到西拉,经常与芬太尼和其他阿片类药物/兴奋剂同时发生.
- 克西拉的患病率在研究期间呈现下降,并且在地理位置上有所不同.
- 莱瓦米索尔 (1.9%) 和美德托米丁 (0.7%) 较少发现,没有显著的同时发生.
结论:
- 全州监测对于了解不断发展的不受监管的药物市场至关重要,特别是关于与伤口相关的药物.
- 药物检查,减伤服务和可访问的伤口护理对于减轻健康风险至关重要.
- 调查结果强调需要综合公共卫生战略来应对药物改的复杂挑战.
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