在接受口服抗凝药的患者的骨骨折后的治疗和结果
Alexander Wilton1, Ayman Sorial1, Tanzeelah Jamadar1
1North West Anglia Foundation Trust, Peterborough, United Kingdom.
Injury
|December 6, 2024
概括
接受抗凝药的骨骨折患者,包括直接口服抗凝药 (DOAC),可以安全地接受手术. 目前的管理政策确保没有增加并发症或死亡风险,尽管剧院时间有轻微的延迟.
科学领域:
- 整形外科手术 整形外科手术
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 治疗口服抗凝药的骨骨折患者的患病率增加,包括DOAC.
- 对这些患者的最佳手术时间和并发症率的不确定性.
研究的目的:
- 为了比较服用抗凝血剂的骨骨折患者的治疗和结果,与不服用抗凝血剂的患者进行比较.
- 评估当前对抗凝血治疗的骨骨折患者手术时间政策的安全性.
主要方法:
- 在7年内对3,707名关节骨折患者进行了回顾性分析.
- 基于抗凝血状态 (华法林,DOAC,没有) 的患者人口统计,并发症和术后结果的比较.
主要成果:
- 在研究期间,DOAC使用量显著增加 (1.4%至11.4%),华法林使用量略有下降 (6.1%至4.7%).
- 接受抗凝药的患者年龄较大,患心房动的可能性更高.
- 与未服用抗凝血剂 (31.1小时) 相比,抗凝血剂患者的治疗时间延迟 (37.9-39.5小时).
- 没有观察到输血率,伤口并发症,术后血红蛋白或30天死亡率的显著差异.
结论:
- 在接受口服抗凝药的患者中,目前的关节骨折手术管理政策是安全的.
- 术后结果,包括死亡率和并发症,不会受到抗凝药状态的不利影响.
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