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早期母亲照顾对青少年非人类灵长类动物焦虑和威胁学习的影响

Elyse L Morin¹, Erin R Siebert², Brittany R Howell³

¹Department of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, United States; Emory National Primate Research Center, Emory University, Atlanta, GA, United States.

Developmental cognitive neuroscience

|December 6, 2024

概括

早期的生活逆境,如母亲虐待 (MALT),增加了 rhesus 子的焦虑. 这项研究发现,MALT会导致青少年持久的情绪失调和模糊的恐惧反应.

科学领域:

神经科学是一个神经科学.
心理学心理学心理学
发展心理学发展心理学

背景情况:

早期的生活不良经历与精神病理学和焦虑障碍有关.
童年虐待可能导致失调的恐惧反应和改变的情绪调节.
在 rhesus 中,母亲虐待 (MALT) 增加了婴儿的情绪反应.

研究的目的:

调查母亲虐待 (MALT) 对青少年 rhesus 子状态焦虑和威胁/安全学习的长期影响.
为了确定MALT是否通过影响恐惧学习或安全信号利用来改变情绪调节.
检查MALT对恐惧条件,暗示歧视和灭绝过程的影响.

主要方法:

使用 rhesus子模型对待母亲的虐待 (MALT).
在25只青少年子中使用一种恐惧调节范式 (AX+/BX-).
测量了声响振幅,以评估基线声响,恐惧强化的声响,威胁/安全歧视,安全信号减弱和灭绝.

主要成果:

母亲虐待 (MALT) 动物表现出更高的基线惊慌失措,表明状态焦虑升高.
在MALT和对照组之间,在威胁学习或威胁/安全提示歧视方面没有发现显著差异.
马尔特动物对有条件的威胁线索表现出普遍的模糊反应,恐惧反应的灭绝受损.

结论:

负面的护理经历,如母亲虐待 (MALT),对青少年情绪调节有持久的负面影响.
母亲虐待 (MALT) 与青少年 rhesus 子的高度状态焦虑和模糊的恐惧条件反应有关.
这些发现与人类儿童虐待相关的情绪失调报告一致.

关键词:

焦虑焦虑是一种焦虑.早期生活中的逆境.恐惧强化的惊吓.婴儿虐待婴儿虐待非人类灵长类的灵长类.

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